Vertically aligned carbon nanofiber arrays record electrophysiological signals from hippocampal slices

被引：99

作者：

Yu, Zhe

McKnight, Timothy E.

Ericson, M. Nance

Melechko, Anatoli V.

Simpson, Michael L.

Morrison, Barclay, III

机构：

[1] Columbia Univ, Dept Biomed Engn, New York, NY 10027 USA

[2] Oak Ridge Natl Lab, Mol Scale Engn & Nanoscale Technol Res Grp, Oak Ridge, TN 37831 USA

[3] Oak Ridge Natl Lab, Monolith Syst Dev Grp, Oak Ridge, TN 37831 USA

[4] Oak Ridge Natl Lab, Ctr Nanophase Mat Sci, Oak Ridge, TN 37831 USA

来源：

NANO LETTERS | 2007年 / 7卷 / 08期

关键词：

CHEMICAL-VAPOR-DEPOSITION; SOURCE DENSITY ANALYSIS; LARGE-SCALE SYNTHESIS; SILICON-BASED ARRAYS; MICROELECTRODE ARRAY; BRAIN-SLICES; BIOCHEMICAL FUNCTIONALIZATION; FIBER MICROELECTRODE; ELECTRODES; STIMULATION;

D O I：

10.1021/nl070291a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Vertically aligned carbon nanofiber (VACNF) electrode arrays were tested for their potential application in recording neuro-electrophysiological activity. We report, for the first time, stimulation and extracellular recording of spontaneous and evoked neuroelectrical activity in organotypic hippocampal slice cultures with ultramicroelectrode VACNF arrays. Because the electrodes are carbon-based, these arrays have potential advantages over metal electrodes and could enable a variety of future applications as precise, informative, and biocompatible neural interfaces.

引用

收藏

页码：2188 / 2195

页数：8

相关论文

共 72 条

[1] CARBON FIBER-REINFORCED CARBON AS A POTENTIAL IMPLANT MATERIAL [J].

ADAMS, D ;

WILLIAMS, DF ;

HILL, J .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1978, 12 (01) :35-42

[2] Electrochemical nanoneedle biosensor based on multiwall carbon nanotube [J].

Boo, H ;

Jeong, RA ;

Park, S ;

Kim, KS ;

An, KH ;

Lee, YH ;

Han, JH ;

Kim, HC ;

Chung, TD .

ANALYTICAL CHEMISTRY, 2006, 78 (02) :617-620

[3] Carbon filaments direct the growth of postlesional plastic axons after spinal cord injury [J].

Chauhan, NB ;

Figlewicz, HM ;

Khan, T .

INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 1999, 17 (03) :255-264

[4] Transfer of flexible arrays of vertically aligned carbon nanofiber electrodes to temperature-sensitive substrates [J].

Fletcher, Benjamin L. ;

McKnight, Timothy E. ;

Melechko, Anatoli V. ;

Hensley, Dale K. ;

Thomas, Darrell K. ;

Ericson, M. Nance ;

Simpson, Michael L. .

ADVANCED MATERIALS, 2006, 18 (13) :1689-+

[5] Biochemical functionalization of vertically aligned carbon nanofibres [J].

Fletcher, Benjamin L. ;

McKnight, Timothy E. ;

Melechko, Anatoli V. ;

Simpson, Michael L. ;

Doktycz, Mitchel J. .

NANOTECHNOLOGY, 2006, 17 (08) :2032-2039

[6] EXPERIMENTAL OPTIMIZATION OF CURRENT SOURCE-DENSITY TECHNIQUE FOR ANURAN CEREBELLUM [J].

FREEMAN, JA ;

NICHOLSON, C .

JOURNAL OF NEUROPHYSIOLOGY, 1975, 38 (02) :369-382

[7] COMMENTS ON MICROELECTRODES [J].

GESTELAND, RC ;

HOWLAND, B ;

LETTVIN, JY ;

PITTS, WH .

PROCEEDINGS OF THE INSTITUTE OF RADIO ENGINEERS, 1959, 47 (11) :1856-1862

[8] Custom-designed high-density conformal planar multielectrode arrays for brain slice electrophysiology [J].

Gholmieh, G ;

Soussou, W ;

Han, M ;

Ahuja, A ;

Hsiao, MC ;

Song, D ;

Tanguay, AR ;

Berger, TW .

JOURNAL OF NEUROSCIENCE METHODS, 2006, 152 (1-2) :116-129

[9] TRANSPARENT INDIUM TIN OXIDE ELECTRODE PATTERNS FOR EXTRACELLULAR, MULTISITE RECORDING IN NEURONAL CULTURES [J].

GROSS, GW ;

WEN, WY ;

LIN, JW .

JOURNAL OF NEUROSCIENCE METHODS, 1985, 15 (03) :243-252

[10] SIMULTANEOUS SINGLE UNIT RECORDING INVITRO WITH A PHOTOETCHED LASER DEINSULATED GOLD MULTI-MICRO-ELECTRODE SURFACE [J].

GROSS, GW .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1979, 26 (05) :273-279

← 1 2 3 4 5 6 7 8 →