A subinhibitory concentration of clarithromycin inhibits Mycobactetium avium biofilm formation

被引：34

作者：

Carter, G

Young, LS

Bermudez, LE

机构：

[1] Oregon State Univ, Coll Vet Med, Dept Biomed Sci, Corvallis, OR 97331 USA

[2] Oregon State Univ, Coll Sci, Dept Microbiol, Corvallis, OR 97331 USA

[3] Calif Pacific Med Ctr, Inst Res, Kuzell Inst, San Francisco, CA USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 12期

关键词：

D O I：

10.1128/AAC.48.12.4907-4910.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Mycobacterium avium causes disseminated infection in immunosuppressed individuals and lung infection in patients with chronic lung diseases. M. avium forms biofilm in the environment and possibly in human airways. Antibiotics with activity against the bacterium could inhibit biofilm formation. Clarithromycin inhibits biofilm formation but has no activity against established biofilm.

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页码：4907 / 4910

页数：4

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