Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere

被引：375

作者：

Lazear, Helen M. ^{[1
]}

Diamond, Michael S. ^{[2
,3
,4
]}

机构：

[1] Univ N Carolina, Dept Microbiol & Immunol, Chapel Hill, NC USA

[2] Washington Univ, Sch Med, Dept Med, Dept Mol Microbiol,Dept Pathol, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Dept Immunol, St Louis, MO USA

[4] Washington Univ, Sch Med, Ctr Human Immunol & Immunotherapy Programs, St Louis, MO USA

来源：

JOURNAL OF VIROLOGY | 2016年 / 90卷 / 10期

关键词：

ENVELOPE PROTEIN GLYCOSYLATION; JAPANESE ENCEPHALITIS-VIRUS; NILE-VIRUS; DENGUE VIRUS; PREGNANT-WOMEN; UNITED-STATES; SEXUAL TRANSMISSION; INTERIM GUIDELINES; FRENCH-POLYNESIA; AEDES-AEGYPTI;

D O I：

10.1128/JVI.00252-16

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of outbreaks accompanied by unexpectedly severe clinical complications brought this virus into the spotlight as causing an infection of global public health concern. In this review, we discuss the history and epidemiology of ZIKV infection, recent outbreaks in Oceania and the emergence of ZIKV in the Western Hemisphere, newly ascribed complications of ZIKV infection, including Guillain-Barre syndrome and microcephaly, potential interactions between ZIKV and dengue virus, and the prospects for the development of antiviral agents and vaccines.

引用

页码：4864 / 4875

页数：12

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