Differential expression of genes that harbor a common regulatory element in Neisseria meningitidis upon contact with target cells

被引：8

作者：

Deghmane, AE ^{[1
]}

Larribe, M ^{[1
]}

Giorgini, D ^{[1
]}

Sabino, D ^{[1
]}

Taha, MK ^{[1
]}

机构：

[1] Inst Pasteur, Unite Neisseria, F-75724 Paris 15, France

来源：

INFECTION AND IMMUNITY | 2003年 / 71卷 / 05期

关键词：

D O I：

10.1128/IAI.71.5.2897-2901.2003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The expression of several genes in Neisseria meningitidis upon contact with epithelial cells was associated with the presence of the contact regulatory elements of Neisseria. These genes are involved in various aspects of meningococcal biology and could be coordinately regulated upon contact with target cells.

引用

页码：2897 / 2901

页数：5

共 13 条

[1] Neisseria gonorrhoeae mutants altered in toxicity to human fallopian tubes and molecular characterization of the genetic locus involved [J].

Arvidson, CG ;

Kirkpatrick, R ;

Witkamp, MT ;

Larson, JA ;

Schipper, CA ;

Waldbeser, LS ;

O'Gaora, P ;

Cooper, M ;

So, M .

INFECTION AND IMMUNITY, 1999, 67 (02) :643-652

[2]

Cartwright K., 1995, Meningococcal Disease, P115

[3] Down-regulation of pili and capsule of Neisseria meningitidis upon contact with epithelial cells is mediated by CrgA regulatory protein [J].

Deghmane, AE ;

Giorgini, D ;

Larribe, M ;

Alonso, JM ;

Taha, MK .

MOLECULAR MICROBIOLOGY, 2002, 43 (06) :1555-1564

[4] Intimate adhesion of Neisseria meningitidis to human epithelial cells is under the control of the crgA gene, a novel LysR-type transcriptional regulator [J].

Deghmane, AE ;

Petit, S ;

Topilko, A ;

Pereira, Y ;

Giorgini, D ;

Larribe, M ;

Taha, MK .

EMBO JOURNAL, 2000, 19 (05) :1068-1078

[5] Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays [J].

Grifantini, R ;

Bartolini, E ;

Muzzi, A ;

Draghi, M ;

Frigimelica, E ;

Berger, J ;

Ratti, G ;

Petracca, R ;

Galli, G ;

Agnusdei, M ;

Giuliani, MM ;

Santini, L ;

Brunelli, B ;

Tettelin, H ;

Rappuoli, R ;

Randazzo, F ;

Grandi, G .

NATURE BIOTECHNOLOGY, 2002, 20 (09) :914-921

[6] ROLES OF PILIN AND PILC IN ADHESION OF NEISSERIA-MENINGITIDIS TO HUMAN EPITHELIAL AND ENDOTHELIAL-CELLS [J].

NASSIF, X ;

BERETTI, JL ;

LOWY, J ;

STENBERG, P ;

OGAORA, P ;

PFEIFER, J ;

NORMARK, S ;

SO, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (09) :3769-3773

[7] Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491 [J].

Parkhill, J ;

Achtman, M ;

James, KD ;

Bentley, SD ;

Churcher, C ;

Klee, SR ;

Morelli, G ;

Basham, D ;

Brown, D ;

Chillingworth, T ;

Davies, RM ;

Davis, P ;

Devlin, K ;

Feltwell, T ;

Hamlin, N ;

Holroyd, S ;

Jagels, K ;

Leather, S ;

Moule, S ;

Mungall, K ;

Quail, MA ;

Rajandream, MA ;

Rutherford, KM ;

Simmonds, M ;

Skelton, J ;

Whitehead, S ;

Spratt, BG ;

Barrell, BG .

NATURE, 2000, 404 (6777) :502-506

[8] THE GENERAL PROTEIN-EXPORT PATHWAY IS DIRECTLY REQUIRED FOR EXTRACELLULAR PULLULANASE SECRETION IN ESCHERICHIA-COLI K12 [J].

PUGSLEY, AP ;

KORNACKER, MG ;

POQUET, I .

MOLECULAR MICROBIOLOGY, 1991, 5 (02) :343-352

[9] The duality of virulence and transmissibility in Neisseria meningitides [J].

Taha, MK ;

Deghmane, AE ;

Antignac, A ;

Zarantonelli, ML ;

Larribe, M ;

Alonso, JM .

TRENDS IN MICROBIOLOGY, 2002, 10 (08) :376-382

[10] Pilus-mediated adhesion of Neisseria meningitidis:: the essential role of cell contact-dependent transcriptional upregulation of the PilC1 protein [J].

Taha, MK ;

Morand, PC ;

Pereira, Y ;

Eugène, E ;

Giorgini, D ;

Larribe, M ;

Nassif, X .

MOLECULAR MICROBIOLOGY, 1998, 28 (06) :1153-1163

← 1 2 →