Cyclophosphamide-induced acute respiratory distress syndrome

被引:6
作者
Brieva, Jorge [1 ]
机构
[1] Mater Misericordiae Univ Hosp, Intens Care Unit, Newcastle, NSW, Australia
关键词
acute respiratory distress syndrome; cyclophosphamide; respiratory failure;
D O I
10.1111/j.1440-1843.2007.01128.x
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Cyclophosphamide is widely used in neoplastic and inflammatory diseases. Although several adverse events have been described with its use, acute and subacute interstitial pneumonitis leading to pulmonary fibrosis is rare and potentially fatal. This case report describes a 64-year-old man who, after the fifth chemotherapy cycle, developed a severe ARDS leading to pulmonary fibrosis in just 30 days.
引用
收藏
页码:769 / 773
页数:5
相关论文
共 48 条
[1]   LATE-ONSET PULMONARY FIBROSIS AND CHEST DEFORMITY IN 2 CHILDREN TREATED WITH CYCLOPHOSPHAMIDE [J].
ALVARADO, CS ;
BOAT, TF ;
NEWMAN, AJ .
JOURNAL OF PEDIATRICS, 1978, 92 (03) :443-446
[2]   USE OF INTERMITTENT, INTRAVENOUS CYCLOPHOSPHAMIDE FOR IDIOPATHIC PULMONARY FIBROSIS [J].
BAUGHMAN, RP ;
LOWER, EE .
CHEST, 1992, 102 (04) :1090-1094
[3]   Case report - Amiodarone and cyclophosphamide: potential for enhanced lung toxicity [J].
Bhagat, R ;
Sporn, TA ;
Long, GD ;
Folz, RJ .
BONE MARROW TRANSPLANTATION, 2001, 27 (10) :1109-1111
[4]   Cardiac and pulmonary toxicity in patients undergoing high-dose chemotherapy for lymphoma and breast cancer: prognostic factors [J].
Brockstein, BE ;
Smiley, C ;
Al-Sadir, J ;
Williams, SF .
BONE MARROW TRANSPLANTATION, 2000, 25 (08) :885-894
[5]   FATAL PULMONARY FIBROSIS OCCURRING DURING TREATMENT WITH CYCLOPHOSPHAMIDE [J].
BURKE, DA ;
STODDART, JC ;
WARD, MK ;
SIMPSON, CGB .
BRITISH MEDICAL JOURNAL, 1982, 285 (6343) :696-696
[6]   Drug-induced and iatrogenic infiltrative lung disease [J].
Camus, P ;
Bonniaud, P ;
Fanton, A ;
Camus, C ;
Baudaun, N ;
Foucher, P .
CLINICS IN CHEST MEDICINE, 2004, 25 (03) :479-+
[7]   Pulmonary toxicity of high-dose chemotherapy for breast cancer: a non-invasive approach to diagnosis and treatment [J].
Chap, L ;
Shpiner, R ;
Levine, M ;
Norton, L ;
Lill, M ;
Glaspy, J .
BONE MARROW TRANSPLANTATION, 1997, 20 (12) :1063-1067
[8]   Combined corticosteroid and cyclophosphamide therapy does not alter survival in idiopathic pulmonary fibrosis [J].
Collard, HR ;
Ryu, JH ;
Douglas, WW ;
Schwarz, MI ;
Curran-Everett, D ;
King, TE ;
Brown, KK .
CHEST, 2004, 125 (06) :2169-2174
[9]  
COOPER JAD, 1986, AM REV RESPIR DIS, V134, P108
[10]  
DIAZGONZALEZ F, 1992, J RHEUMATOL, V19, P325