The role of extracellular matrix in CNS regeneration

被引：374

作者：

Busch, Sarah A. ^{[1
]}

Silver, Jerry ^{[1
]}

机构：

[1] Case Western Reserve Univ, Sch Med, Dept Neurosci, Cleveland, OH 44106 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2007年 / 17卷 / 01期

关键词：

D O I：

10.1016/j.conb.2006.09.004

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Chondroitin sulfate proteoglycans are the principal inhibitory component of glial scars, which form after damage to the adult central nervous system and act as a barrier to regenerating axons. Recent findings have furthered our understanding of the mechanisms that result in a failure of regeneration after spinal cord injury and suggest that a multipartite approach will be required to facilitate long-distance regeneration and functional recovery.

引用

页码：120 / 127

页数：8

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