Reaction of mercaptoacetate and halides containing activated methylenes with thiocarbamoylimidates: A novel approach to the synthesis of aminothiazole derivatives

被引：7

作者：

Dridi, K ^{[1
]}

El Efrit, ML ^{[1
]}

Baccar, B ^{[1
]}

Zantour, H ^{[1
]}

机构：

[1] Fac Sci Tunis, Dept Chim, Organ Synth Lab, Tunis 1060, Tunisia

来源：

SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 01期

关键词：

D O I：

10.1080/00397919808005086

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of N-thiocarbamoylimidates (1) under bar with methyl thioglycolate leads to the formation of 4-arylamino-5-methoxycarbonylthiazoles (2) under bar. The condensation of the same imidates (1) under bar on ethyl bromoacetate, benzyl bromide and chloroacetonitrile provides the corresponding 2-arylaminothiazoles (4) under bar.

引用

页码：167 / 174

页数：8

共 13 条

[1]

BELLASSOUED M, 1986, B SOC CHIM BELG, V95, P65

[2]

CHARLES GB, Patent No. 9204353

[3]

CURRIE RB, Patent No. 2850504

[4]

EIJI N, Patent No. 04112890

[5]

El Efrit M. L., 1993, J SOC CHIM TUNISIE, V3, P361

[6] Synthesis of benzoxazines, 3,4-dihydroquinazolines and quinazolinethiones. [J].

ElEfrit, ML ;

Hajjem, B ;

Zantour, H ;

Baccar, B .

SYNTHETIC COMMUNICATIONS, 1996, 26 (17) :3167-3173

[7]

HAJJEM B, 1995, INDIAN J CHEM B, V34, P330

[8] ACTION OF ORGANOMETALLIC COMPOUNDS ON N-CYANOMETHYLIMIDATE - NEW SYNTHETIC METHODE OF OXAZOLE [J].

HAJJEM, B ;

BACCAR, B .

SYNTHETIC COMMUNICATIONS, 1991, 21 (14) :1501-1509

[9]

HARIZI A, UNPUB

[10]

HYEK LK, Patent No. 10123

← 1 2 →