Selective functionalization of alkanes by transition-metal boryl complexes

被引:225
作者
Waltz, KM
Hartwig, JF
机构
[1] Department of Chemistry, Yale University, New Haven
关键词
D O I
10.1126/science.277.5323.211
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Simple transition-metal complexes of the formula Cp*M(CO)(n)BR2 [Cp* = C-5(CH3)(5)] containing an electrophilic, covalently bound main-group ligand react with alkanes and release products resulting from selective functionalization of an alkane at the terminal position. These reactions produce alkylboronate esters, which are common reagents in organic synthesis, Thus, the boryl complexes are rare chemical reagents that react selectivity at the terminal position of an alkane to provide simple functionalized products. Mechanistic analysis shows that ligand dissociation is induced photochemically and that thermal reaction of the resulting intermediate occurs with alkanes.
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页码:211 / 213
页数:3
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