Hearing - Channel at the hair's end

被引：4

作者：

Ashmore, J

机构：

[1] UCL, Dept Physiol, London WC1E 6BT, England

[2] UCL, Ear Inst, London WC1E 6BT, England

来源：

NATURE | 2004年 / 432卷 / 7018期

关键词：

D O I：

10.1038/432685a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Ion channels controlled by sound underlie the sense of hearing. Having long eluded researchers, the first such mammalian channel has now been identified in the mouse inner ear.

引用

页码：685 / 686

页数：2

共 15 条

[1]

Beech DJ, 2004, J PHYSIOL-LONDON, V559, P685, DOI 10.1113/jphysiol.2004.068734

[2] TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells [J].

Corey D.P. ;

Garcia-Añoveros J. ;

Holt J.R. ;

Kwan K.Y. ;

Lin S.-Y. ;

Vollrath M.A. ;

Amalfitano A. ;

Cheung E.L.-M. ;

Derfler B.H. ;

Duggan A. ;

Géléoc G.S.G. ;

Gray P.A. ;

Hoffman M.P. ;

Rehm H.L. ;

Tamasauskas D. ;

Zhang D.-S. .

Nature, 2004, 432 (7018) :723-730

[3] Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice [J].

Di Palma, F ;

Belyantseva, IA ;

Kim, HJ ;

Vogt, TF ;

Kachar, B ;

Noben-Trauth, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (23) :14994-14999

[4] Two interdependent TRPV channel subunits, inactive and Nanchung, mediate hearing in Drosophila [J].

Gong, ZF ;

Son, WS ;

Chung, YD ;

Kim, JW ;

Shin, DW ;

McClung, CA ;

Lee, Y ;

Lee, HW ;

Chang, DJ ;

Kaang, BK ;

Cho, HW ;

Oh, U ;

Hirsh, J ;

Kernan, MJ ;

Kim, CS .

JOURNAL OF NEUROSCIENCE, 2004, 24 (41) :9059-9066

[5] Mechanoelectrical transduction of adult outer hair cells studied in a gerbil hemicochlea [J].

He, DZZ ;

Jia, SP ;

Dallos, P .

NATURE, 2004, 429 (6993) :766-770

[6] Hypothesis: A helix of ankyrin repeats of the NOMPIC-TRP ion channel is the gating spring of mechanoreceptors [J].

Howard, J ;

Bechstedt, S .

CURRENT BIOLOGY, 2004, 14 (06) :R224-R226

[7] Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1 [J].

Jordt, SE ;

Bautista, DM ;

Chuang, HH ;

McKemy, DD ;

Zygmunt, PM ;

Högestätt, ED ;

Meng, ID ;

Julius, D .

NATURE, 2004, 427 (6971) :260-265

[8] High-resolution structure of hair-cell tip links [J].

Kachar, B ;

Parakkal, M ;

Kurc, M ;

Zhao, Y ;

Gillespie, PG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (24) :13336-13341

[9] A TRPV family ion channel required for hearing in Drosophila [J].

Kim, J ;

Chung, YD ;

Park, DY ;

Choi, SK ;

Shin, DW ;

Soh, H ;

Lee, HW ;

Son, W ;

Yim, J ;

Park, CS ;

Kernan, MJ ;

Kim, C .

NATURE, 2003, 424 (6944) :81-84

[10] TRP ion channels in the nervous system [J].

Moran, MM ;

Xu, HX ;

Clapham, DE .

CURRENT OPINION IN NEUROBIOLOGY, 2004, 14 (03) :362-369

← 1 2 →