A novel synthesis of β-trifluoromethyl-substituted isoserine via intramolecular rearrangement of imino ethers

被引：44

作者：

Uneyama, K ^{[1
]}

Hao, JA ^{[1
]}

Amii, H ^{[1
]}

机构：

[1] Okayama Univ, Fac Engn, Dept Appl Chem, Okayama 7000082, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 23期

关键词：

D O I：

10.1016/S0040-4039(98)00663-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The methodology for the construction of beta-trifluoromethyl-substituted isoserine is reported The fluorinated alpha-hydroxy-beta-imino esters which are the precursors to amino add derived isoserine were formed firstly via a base catalyzed intramolecular rearrangement of imino ethers, and the subsequent conversions of these compounds resulted in the formation of the designed isoserines and the related fluorinated compounds. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：4079 / 4082

页数：4

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