Analysis of virulence factors in cases of enterococcal endocarditis

被引：25

作者：

Baldassarri, L

Creti, R

Arciola, CR

Montanaro, L

Venditti, M

Di Rosa, R

机构：

[1] Ist Super Sanita, Dipartimento Malattie Infett Parassitarie & Immun, Lab Malattie Batteriche Resp & Sistemat, I-00161 Rome, Italy

[2] Ist Ortoped Rizzoli, Bologna, Italy

[3] Univ Roma La Sapienza, Dipartimento Med Clin, Rome, Italy

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2004年 / 10卷 / 11期

关键词：

endocarditis; Enterococcus faecalis; virulence factors;

D O I：

10.1111/j.1469-0691.2004.00999.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Eleven isolates of Enterococcus faecalis causing endocarditis were screened for possible virulence factors with PCR and phenotypic assays. The gene coding for the enterococcal surface protein (esp) was detected in one isolate only, and haemolysin was produced by two isolates. Aggregation substance, biofilm formation and gelatinase were present in seven, nine and eight isolates, respectively. Predisposing factors, particularly hospitalisation and multiple antibiotic therapy, appeared to be more relevant to the development of enterococcal endocarditis following bloodstream infections than the pattern of virulence factors.

引用

页码：1006 / 1008

页数：3

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