High rate of fatal cases of pediatric septicemia caused by gram-negative bacteria with extended-spectrum beta-lactamases in Dar es Salaam, Tanzania

被引：138

作者：

Blomberg, B ^{[1
]}

Jureen, R

Manji, KP

Tamim, BS

Mwakagile, DSM

Urassa, WK

Fataki, M

Msangi, V

Tellevik, MG

Maselle, SY

Langeland, N

机构：

[1] Univ Bergen, Ctr Int Hlth, N-5021 Bergen, Norway

[2] Univ Bergen, Inst Med, N-5021 Bergen, Norway

[3] Haukeland Hosp, N-5021 Bergen, Norway

[4] Muhimbili Univ, Coll Hlth Sci, Dept Paediat & Child Hlth, Dar Es Salaam, Tanzania

[5] Muhimbili Univ, Coll Hlth Sci, Dept Microbiol & Immunol, Dar Es Salaam, Tanzania

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2005年 / 43卷 / 02期

关键词：

D O I：

10.1128/JCM.43.2.745-749.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Extended-spectrum beta-lactamases (ESBLs) were present in high proportions of Escherichia coli (25% [9 of 36]) and Klebsiella pneumoniae isolates (17% [9 of 52]) causing pediatric septicemia at a tertiary hospital in Tanzania. Patients with septicemia due to ESBL-producing organisms had a significantly higher fatality rate than those with non-ESBL isolates (71% versus 39%, P = 0.039). This is the first report of the CTX-M-15 genotype of ESBLs on the African continent and the first observation of SHV-12 genotype in an isolate of Salmonella enterica serotype Newport.

引用

页码：745 / 749

页数：5

共 22 条

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