The American-European Consensus Conference on ARDS, Part 2 - Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling

被引：275

作者：

Artigas, A ^{[1
]}

Bernard, GR

Carlet, J

Dreyfuss, D

Gattinoni, L

Hudson, L

Lamy, M

Marini, JJ

Matthay, MA

Pinsky, MR

Spragg, R

Suter, PM

Blanch, L

Burchardi, H

Hedenstierna, C

Lemaire, F

Roussos, C

Mancebo, J

Morris, A

Pesenti, A

Rossi, A

Van Asbeck, BS

Brigham, KL

Dhainaut, JF

Fowler, AA

Hyers, TM

Morel, D

Rodriguez-Roisin, R

Schaller, MD

Hemmer, M

Torres, A

Villar, J

Vincent, JL

Leeper, K

Meyrick, B

Oppenheimer, L

Reid, L

Murray, JF

Bihari, D

Bosken, C

Goris, J

Johanson, WJ

Lanken, PN

Le Gall, JR

Morris, AH

Rinaldo, J

Pattishal, EN

机构：

[1] Sabadell Hosp, Sabadell, Spain

[2] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA

[3] Univ Minnesota, Minneapolis, MN USA

[4] Louis Mourier Hosp, Colombes, France

[5] Univ Gottingen, Gottingen, Germany

[6] Univ Hosp, Uppsala, Sweden

[7] Henri Mondor Hosp, Creteil, France

[8] Evangelismos Med Ctr, Athens, Greece

[9] Hosp St Pau Hosp, Barcelona, Spain

[10] Latter Day St Hosp, Salt Lake City, UT USA

[11] Univ Milan, Monza, Italy

[12] Hosp Maggiore di Borgo Trento, Verona, Italy

[13] Univ Hosp Sart Tilman, Liege, Belgium

[14] Univ Utrecht, Utrecht, Netherlands

[15] Hop Cochin, Paris, France

[16] Virginia Commonwealth Univ Med Coll Virginia, Richmond, VA USA

[17] St Louis Univ, St Louis, MO 63103 USA

[18] Univ Cantonal Hosp, Ceneve, Switzerland

[19] Hosp Clin Barcelona, Barcelona, Spain

[20] Univ Lausanne, Lausanne, Switzerland

[21] Univ Pittsburgh, Pittsburgh, PA USA

[22] Univ Hosp Luxembourg, Luxembourg, Luxembourg

[23] Hosp Candelaria, Santa Cruz De Tenerife, Spain

[24] Erasme Univ Hosp, Brussels, Belgium

[25] Univ Calif San Francisco, San Francisco, CA 94143 USA

[26] Univ Milan, Milan, Italy

[27] Univ Tennessee, Memphis, TN USA

[28] Univ Manitoba, Winnipeg, MB, Canada

[29] Harvard Med Sch, Childrens Hosp, Boston, MA 02115 USA

[30] St Josephs Hosp, Paris, France

[31] Univ Washington, Seattle, WA 98195 USA

[32] Univ Calif San Diego, San Diego, CA 92103 USA

[33] Guys Hosp, London, England

[34] NHLBI, NIH, Div Lung Dis, Bethesda, MA USA

[35] Univ Hosp St Radboud, Nijmegen, Netherlands

[36] New Jersey Sch Med, Newark, NJ USA

[37] Univ Penn, Philadelphia, PA 19104 USA

[38] St Louis Hosp, Paris, France

[39] Burroughs Wellcome, Winston Salem, NC USA

来源：

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 1998年 / 157卷 / 04期

关键词：

D O I：

10.1164/ajrccm.157.4.ats2-98

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The acute respiratory distress syndrome (ARDS) continues as a contributor to the morbidity and mortality of patients in intensive care units throughout the world, imparting tremendous human and financial costs. During the last 10 years there has been a decline in ARDS mortality without a clear explanation. The American-European Consensus Committee on ARDS was formed to re-evaluate the standards for the ICU care of patients with acute lung injury (ALI), with regard to ventilatory strategies, the more promising pharmacologic agents, and the definition and quantification of pathologic features of ALI that require resolution. It was felt that the definition of strategies for the clinical design and coordination of studies between centers and continents was becoming increasingly important to facilitate the study of various new therapies for ARDS.

引用

页码：1332 / 1347

页数：16

共 189 条

[1] EFFICACY AND SAFETY OF MONOCLONAL-ANTIBODY TO HUMAN TUMOR-NECROSIS-FACTOR-ALPHA IN PATIENTS WITH SEPSIS SYNDROME - A RANDOMIZED, CONTROLLED, DOUBLE-BLIND, MULTICENTER CLINICAL-TRIAL [J].