Absence of teratogenicity of sirolimus used during early pregnancy in a liver transplant recipient

被引：36

作者：

Jankowska, I ^{[1
]}

Oldakowska-Jedynak, U

Jabiry-Zieniewicz, Z

Cyganek, A

Pawlowska, J

Teisseyre, M

Kalicinski, P

Markiewicz, M

Paczek, L

Socha, J

机构：

[1] Childrens Mem Hlth Inst, Dept Gastroenterol Hepatol & Immunol, Warsaw, Poland

[2] Univ Med Sch, Dept Immunol Transplantat & Internal Dis, Warsaw, Poland

[3] Univ Med Sch, Dept Obstet & Gynecol, Warsaw, Poland

[4] Childrens Mem Hlth Inst, Dept Pediat Surg & Organ Transplantat, Warsaw, Poland

来源：

TRANSPLANTATION PROCEEDINGS | 2004年 / 36卷 / 10期

关键词：

D O I：

10.1016/j.transproceed.2004.11.102

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We describe the case of successful delivery in a 21-year-old woman who became pregnant 3 years after liver transplantation and who received sirolimus during the first 6 weeks of gestation. Sirolimus was discontinued when ultrasonography revealed a pregnancy, she was switched to tacrolimus and prednisone was continued. The course of pregnancy was uneventful; there were no signs or symptoms of graft rejection. Due to fetal intrauterine threatening asphyxia the pregnancy was concluded by cesearean section in the 39th gestational week, delivering a healthy, 2950 g, Apgar 10, female infant.

引用

页码：3232 / 3233

页数：2