The prothrombin 20210 A allele is frequently coinherited in young carriers of the factor V Arg 506 to Gln mutation with venous thrombophilia

被引：53

作者：

Ehrenforth, S ^{[1
]}

Ludwig, G

Klinke, S

Krause, M

Scharrer, I

机构：

[1] Univ Hosp, Dept Internal Med, Frankfurt, Germany

[2] Univ Hosp, Dept Pediat, Munster, Germany

来源：

BLOOD | 1998年 / 91卷 / 06期

关键词：

D O I：

10.1182/blood.V91.6.2209

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2209 / 2210

页数：2

共 20 条

[1] The A20210 allele of the prothrombin gene is not frequently associated with the factor V Arg 506 to Gln mutation in thrombophilic families [J].

AlhencGelas, M ;

LeCamDuchez, V ;

Emmerich, J ;

Frebourg, T ;

Fiessinger, JN ;

Borg, JY ;

Aiach, M .

BLOOD, 1997, 90 (04) :1711-1711

[2] MUTATION IN BLOOD-COAGULATION FACTOR-V ASSOCIATED WITH RESISTANCE TO ACTIVATED PROTEIN-C [J].

BERTINA, RM ;

KOELEMAN, BPC ;

KOSTER, T ;

ROSENDAAL, FR ;

DIRVEN, RJ ;

DERONDE, H ;

VANDERVELDEN, PA ;

REITSMA, PH .

NATURE, 1994, 369 (6475) :64-67

[3] Risk of venous thromboembolism associated with a G to A transition at position 20210 in the 3'-untranslated region of the prothrombin gene [J].

Brown, K ;

Luddington, R ;

Williamson, D ;

Baker, P ;

Baglin, T .

BRITISH JOURNAL OF HAEMATOLOGY, 1997, 98 (04) :907-909

[4] The prothrombin gene G20210A variant: Prevalence in a UK anticoagulant clinic population [J].

Cumming, AM ;

Keeney, S ;

Salden, A ;

Bhavnani, M ;

Shwe, KH ;

Hay, CRM .

BRITISH JOURNAL OF HAEMATOLOGY, 1997, 98 (02) :353-355

[5] FAMILIAL THROMBOPHILIA DUE TO A PREVIOUSLY UNRECOGNIZED MECHANISM CHARACTERIZED BY POOR ANTICOAGULANT RESPONSE TO ACTIVATED PROTEIN-C - PREDICTION OF A COFACTOR TO ACTIVATED PROTEIN-C [J].

DAHLBACK, B ;

CARLSSON, M ;

SVENSSON, PJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (03) :1004-1008

[6]

Ehrenforth S, 1998, THROMB HAEMOSTASIS, V79, P684

[7] INCIDENCE OF ACTIVATED PROTEIN-C RESISTANCE CAUSED BY THE ARG-506 GLN MUTATION IN FACTOR-V IN 113 UNRELATED SYMPTOMATIC PROTEIN C-DEFICIENT PATIENTS [J].

GANDRILLE, S ;

GREENGARD, JS ;

ALHENCGELAS, M ;

JUHANVAGUE, I ;

ABGRALL, JF ;

JUDE, B ;

GRIFFIN, JH ;

AIACH, M .

BLOOD, 1995, 86 (01) :219-224

[8] ACTIVATED PROTEIN-C RESISTANCE CAUSED BY ARG506GLN MUTATION IN FACTOR VA [J].

GREENGARD, JS ;

SUN, X ;

XU, X ;

FERNANDEZ, JA ;

GRIFFIN, JH ;

EVATT, B .

LANCET, 1994, 343 (8909) :1361-1362

[9]

Hillarp A, 1997, THROMB HAEMOSTASIS, V78, P990

[10]

KOELEMAN BPC, 1995, THROMB HAEMOSTASIS, V74, P580

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