Solution-phase synthesis of combinatorial libraries designed to modulate protein-protein or protein-DNA interactions

被引：22

作者：

Boger, DL

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 2003年 / 11卷 / 08期

关键词：

D O I：

10.1016/S0968-0896(03)00031-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A short personal perspective on the development of an approach to the solution-phase synthesis of combinatorial libraries for modulating cellular signaling by inhibiting, promoting, or mimicking protein-protein or protein-DNA interactions is provided. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

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页码：1607 / 1613

页数：7

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