Highly enantioselective approach to indolizidines:: Preparation of (+)-(1S,8aS)-1-hydroxyindolizidine and (-)-slaframine

被引：68

作者：

Pourashraf, M ^{[1
]}

Delair, P ^{[1
]}

Rasmussen, MO ^{[1
]}

Greene, AE ^{[1
]}

机构：

[1] Univ Grenoble 1, LEDSS, F-38041 Grenoble, France

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 65卷 / 21期

关键词：

D O I：

10.1021/jo0005621

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly stereoselective approach to (-)-slaframine and its probable biosynthetic precursor (+)-(1S,8aS)-1-hydroxyindolizidine has been developed based on a diastereofacially selective cycloaddition of dichloroketene with achiral dienol ether.

引用

页码：6966 / 6972

页数：7

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