Investigation of haemolytic and complexation properties of γ-cyclodextrin carbonate derivatives

被引：7

作者：

Trotta, F

Cavalli, R

Trotta, M

机构：

[1] Univ Turin, Dipartimento Chim, IFM, I-10125 Turin, Italy

[2] Univ Turin, Dipartimento Sci & Tecnol Farmaco, I-10125 Turin, Italy

来源：

JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY | 2002年 / 44卷 / 1-4期

关键词：

diazepam; flurbiprofen; haemolysis; progesterone; solubilising agents;

D O I：

10.1023/A:1023013206635

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New alkyl carbonates of gamma-cyclodextrin have been obtained. These derivatives show lower haemolytic effect than the parent gamma-cyclodextrin. The complexation behaviour was tested with three important drugs, namely: progesterone, diazepam and flurbiprofen. DSC analyses were consistent with the inclusion complex formation.

引用

页码：345 / 346

页数：2