Pathophysiology of obstructive airways disease

被引:28
作者
Gurney, JW [1 ]
机构
[1] Univ Nebraska, Med Ctr, Dept Radiol, Omaha, NE 68198 USA
关键词
D O I
10.1016/S0033-8389(05)70005-1
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Chronic obstructive pulmonary disease is a group of disorders that have in common abnormal airway structure that results in obstruction to air-flow. In emphysema, obstruction is thought to be due to the loss of normal elastic tension in the lung parenchyma. Cigarette smoke is the most important cause of emphysema. Injurious agents, either in the gas or particulate phase, incite a proteolytic reaction in the lung. The type of emphysema and its topographic distribution in the lung stem from normal physiologic processes that concentrate the cigarette puff both within the lung and within the secondary pulmonary lobule.
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页码:15 / +
页数:14
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