In genetic control of disease, does 'race' matter?

被引:45
作者
Goldstein, DB
Hirschhorn, JN
机构
[1] UCL, Dept Biol, Galton Labs, London WC1E 6BT, England
[2] Harvard Univ, Childrens Hosp, Sch Med, Div Genet & Endocrinol, Boston, MA 02115 USA
[3] Harvard Univ, Boston, MA 02115 USA
[4] Broad Inst MIT, Program Med & Populat Genet, Boston, MA USA
关键词
D O I
10.1038/ng1204-1243
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
As geneticists begin to identify gene variants associated with common diseases and responses to treatment, it is increasingly important to determine whether these variants have consistent effects across different 'racial' or 'ethnic' groups. Until recently, too little was known about either disease genetics or pharmacogenetics to make a detailed assessment. Now, a new study reviewing 43 disease-associated gene variants suggests that the effects of gene variants may be largely consistent across different 'racial' or 'ethnic' groups.
引用
收藏
页码:1243 / 1244
页数:2
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