Cerebral activation during bicycle movements in man

被引:161
作者
Christensen, LOD
Johannsen, P
Sinkjær, T
Petersen, N
Pyndt, HS
Nielsen, JB
机构
[1] Univ Copenhagen, Dept Med Physiol, DK-2200 Copenhagen N, Denmark
[2] Aarhus Univ Hosp, PET Ctr, DK-8000 Aarhus, Denmark
[3] Aalborg Univ, Ctr Sensorimotor Interact, Aalborg, Denmark
关键词
bicycling; locomotion; motor cortex; positron emission tomography;
D O I
10.1007/s002210000493
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The cerebral activation during bicycle movements was investigated by oxygen-15-labelled H2O positron emission tomography (PET) in seven healthy human subjects. Compared to rest active bicycling significantly activated sites bilaterally in the primary sensory cortex, primary motor cortex (M1) and supplementary motor cortex (SMA) as well as the anterior part of cerebellum. Comparing passive bicycling movements with rest, an almost equal activation was observed. Subtracting passive from active bicycle movements, significant activation was only observed in the leg area of the primary motor cortex and the precuneus, but not in the primary sensory cortex (S1). The M1 activation was positively correlated (alpha =0.75-0.85, t=6.4, P<10(-5)) with the rate of the active bicycle movements. Imagination of bicycle movements compared to rest activated bilaterally sites in the SMA. It is suggested that the higher motor centres, including the primary and supplementary motor cortices as well as the cerebellum, take an active part in the generation and control of rhythmic motor tasks such as bicycling.
引用
收藏
页码:66 / 72
页数:7
相关论文
共 36 条
[1]  
[Anonymous], 1958, PHYSL PATHOLOGY CERE
[2]   DISCHARGES OF PURKINJE-CELLS IN THE PARAVERMAL PART OF THE CEREBELLAR ANTERIOR LOBE DURING LOCOMOTION IN THE CAT [J].
ARMSTRONG, DM ;
EDGLEY, SA .
JOURNAL OF PHYSIOLOGY-LONDON, 1984, 352 (JUL) :403-424
[3]   DISCHARGES OF NUCLEUS INTERPOSITUS NEURONS DURING LOCOMOTION IN THE CAT [J].
ARMSTRONG, DM ;
EDGLEY, SA .
JOURNAL OF PHYSIOLOGY-LONDON, 1984, 351 (JUN) :411-432
[4]   DISCHARGES OF PYRAMIDAL TRACT AND OTHER MOTOR CORTICAL-NEURONS DURING LOCOMOTION IN THE CAT [J].
ARMSTRONG, DM ;
DREW, T .
JOURNAL OF PHYSIOLOGY-LONDON, 1984, 346 (JAN) :471-&
[5]  
ARMSTRONG DM, 1988, J PHYSIOL-LONDON, V405, P1, DOI 10.1113/jphysiol.1988.sp017319
[6]   ACTIVITY OF CEREBELLAR PURKINJE-CELLS DURING FICTITIOUS SCRATCH REFLEX IN THE CAT [J].
ARSHAVSKY, YI ;
ORLOVSKY, GN ;
POPOVA, LB .
BRAIN RESEARCH, 1984, 290 (01) :33-41
[7]   INVOLUNTARY STEPPING AFTER CHRONIC SPINAL-CORD INJURY - EVIDENCE FOR A CENTRAL RHYTHM GENERATOR FOR LOCOMOTION IN MAN [J].
CALANCIE, B ;
NEEDHAMSHROPSHIRE, B ;
JACOBS, P ;
WILLER, K ;
ZYCH, G ;
GREEN, BA .
BRAIN, 1994, 117 :1143-1159
[8]   Evidence suggesting that a transcortical reflex pathway contributes to cutaneous reflexes in the tibialis anterior muscle during walking in man [J].
Christensen, LOD ;
Morita, H ;
Petersen, N ;
Nielsen, J .
EXPERIMENTAL BRAIN RESEARCH, 1999, 124 (01) :59-68
[9]   AUTOMATIC 3D INTERSUBJECT REGISTRATION OF MR VOLUMETRIC DATA IN STANDARDIZED TALAIRACH SPACE [J].
COLLINS, DL ;
NEELIN, P ;
PETERS, TM ;
EVANS, AC .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1994, 18 (02) :192-205
[10]   LOCOMOTOR CONTROL IN MACAQUE MONKEYS [J].
EIDELBERG, E ;
WALDEN, JG ;
NGUYEN, LH .
BRAIN, 1981, 104 (DEC) :647-663