Onset of coeliac disease during treatment with interferon for chronic hepatitis C

被引：94

作者：

Cammarota, G ^{[1
]}

Cuoco, L ^{[1
]}

Cianci, R ^{[1
]}

Pandolfi, F ^{[1
]}

Gasbarrini, G ^{[1
]}

机构：

[1] Univ Cattolica Sacro Cuore, Dept Internal Med & Gastroenterol, I-00168 Rome, Italy

来源：

LANCET | 2000年 / 356卷 / 9240期

关键词：

D O I：

10.1016/S0140-6736(00)02880-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The immunomodulatory properties of interferon may concur to precipitate or worsen an underlying autoimmune disorders. We report the cases of two men who displayed the various features of coeliac disease during a treatment with alpha -interferon tin one case associated with ribavirin) for chronic hepatitis C. The patients stopped the interferon treatment and the symptoms and histological disorders improved after a gluten-free diet. alpha -interferon is available wordwide for treatment of chronic viral hepatitis. Before treatment with this drug, the patients would have to be monitored for coeliac disease.

引用

页码：1494 / 1495

页数：2

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