Thymidine-dependent small-colony variants of Staphylococcus aureus exhibit gross morphological and ultrastructural changes consistent with impaired cell separation

被引：76

作者：

Kahl, BC

Belling, G

Reichelt, R

Herrmann, M

Proctor, RA

Peters, G

机构：

[1] Univ Muenster Hosp, Inst Med Microbiol, Munster, Germany

[2] Univ Muenster Hosp, Inst Med Phys & Biophys, Munster, Germany

[3] Univ Saarland, Inst Microbiol & Hyg, D-6650 Homburg, Germany

[4] Univ Wisconsin, Sch Med, Dept Med & Med Microbiol Immunol, Madison, WI USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2003年 / 41卷 / 01期

关键词：

D O I：

10.1128/JCM.41.1.410-413.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Thymidine-dependent small-colony variants (SCV) of Staphylococcus aureus exhibited unusual colony morphology with "fried-egg" or pinpoint white colonies on agar plates and pleomorphic cocci as determined by Gram staining. Electron microscopy revealed enlarged cocci with incomplete or multiple cross walls consistent with impaired cell separation. Fried-egg SCV phenotypes could be reversed by thymidine supplementation.

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页码：410 / 413

页数：4

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