Around the world of DNA damage INO80 days

被引:16
作者
Cairns, BR [1 ]
机构
[1] Univ Utah, Sch Med, Howard Hughes Med Inst, Salt Lake City, UT 84112 USA
[2] Univ Utah, Sch Med, Dept Oncol Sci, Salt Lake City, UT 84112 USA
关键词
D O I
10.1016/j.cell.2004.12.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
DNA damage is detected and repaired in the context of chromatin. In this issue of Cell, van Attikum et al. (2004) and Morrison et al. (2004) demonstrate that double-stranded break repair involves the recruitment of a specialized chromatin remodeling complex, INO80, through an interaction with phosphorylated histone H2A.
引用
收藏
页码:733 / 735
页数:3
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