Variation in susceptibility of bloodstream isolates of candida glabrata to fluconazole according to patient age and geographic location

被引:71
作者
Pfaller, MA
Messer, SA
Boyken, L
Tendolkar, S
Hollis, RJ
Diekema, DJ
机构
[1] Univ Iowa, Roy J Lucille A Carver Coll Med, Dept Pathol, Div Med Microbiol, Iowa City, IA 52242 USA
[2] Univ Iowa, Roy J Lucille A Carver Coll Med, Dept Med, Div Med Microbiol, Iowa City, IA 52242 USA
[3] Univ Iowa, Coll Publ Hlth, Dept Epidemiol, Iowa City, IA 52242 USA
关键词
D O I
10.1128/JCM.41.5.2176-2179.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We examined the susceptibilities to fluconazole of 559 bloodstream infection isolates of Candida glabrata and grouped the isolates by patient age and geographic location within the United States. Susceptibility of C glabrata to fluconazole was lowest in the Pacific (44%) and East South Central (47%) regions and was highest in the West South Central region (82%) (regions are as designated by the U.S. Bureau of the Census). Isolates from pediatric patients were virtually all susceptible to fluconazole, whereas the highest frequency of resistance was observed in isolates from patients 16 to 64 years of age.
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页码:2176 / 2179
页数:4
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