Developing a Case Study Model for Successful Translation of Stem Cell Therapies

被引：20

作者：

Trounson, Alan ^{[1
]}

Baum, Elona ^{[1
]}

Gibbons, Don ^{[1
]}

Tekamp-Olson, Patricia ^{[1
]}

机构：

[1] Calif Inst Regenerat Med, San Francisco, CA 94107 USA

来源：

CELL STEM CELL | 2010年 / 6卷 / 06期

关键词：

D O I：

10.1016/j.stem.2010.05.008

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Cell therapies derived from pluripotent stem cells are entering the preclinical and early clinical development phase, but eventual translation faces many challenges. We describe a new approach by California to form global public-private "disease team" partnerships to enable new clinical opportunities to be evaluated in the complex regulatory environment.

引用

页码：513 / 516

页数：4

共 9 条

[1]

[Anonymous], 2008, Medical research: What's it worth? Estimating the economic benefits from medical research in the UK

[2]

*BRAINL INC, 2010, WHIT PAP SEAML LIF S

[3]

*CAMBR HLTH I, 2010, C 2 ANN COLL INN BIO

[4] Clinical Translation of Stem Cell Therapies: A Bridgeable Gap [J].

Cuende, Natividad ;

Izeta, Ander .

CELL STEM CELL, 2010, 6 (06) :508-512

[5]

KLEIN RN, 2010, DELIVERY RE IN PRESS

[6] Pharma's Developing Interest in Stem Cells [J].

McKernan, Ruth ;

McNeish, John ;

Smith, Devyn .

CELL STEM CELL, 2010, 6 (06) :517-520

[7] Lessons from 60 years of pharmaceutical innovation [J].

Munos, Bernard .

NATURE REVIEWS DRUG DISCOVERY, 2009, 8 (12) :959-968

[8]

Murphy KM, 2003, MEASURING THE GAINS FROM MEDICAL RESEARCH, P41

[9] Industry perceptions of barriers to commercialization of regenerative medicine products in the UK [J].

Plagnol, Anke C. ;

Rowley, Emma ;

Martin, Paul ;

Livesey, Finbarr .

REGENERATIVE MEDICINE, 2009, 4 (04) :549-559

← 1 →