Laser interference lithography micropatterning as a new and efficient technique for of biopolymer surface

被引:68
作者
Yu, FY [1 ]
Li, P
Shen, H
Mathur, S
Lehr, CM
Bakowsky, U
Mücklich, F
机构
[1] Univ Saarland, Dept Mat Sci, D-66123 Saarbrucken, Germany
[2] Univ Saarland, Dept Biopharmaceut & Pharmaceut Technol, D-66123 Saarbrucken, Germany
[3] Leibniz Inst New Mat, CVD Div, D-66041 Saarbrucken, Germany
[4] Univ Marburg, Dept Pharmaceut, D-35032 Marburg, Germany
关键词
laser interference lithography; micropatterning; poly(ethylene terephthalate); Thermanox (R); cell adhesion; x-ray photoelectron microscopy;
D O I
10.1016/j.biomaterials.2004.07.021
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Laser interference lithography (LIL) is a straightforward technique to prepare linear micropatterns for regulating cellular adhesion behaviors on polymer substratum. This process is based on selective laser ablation directly duplicating the interference patterns of two or more coherent laser beams onto the polymer surface. Micropatterns prepared by LIL on poly(ethylene terephthalate) and Thermanox((R)) were characterized using atomic force microscopy (AFM) and white light interferometer while the chemical surface modification induced by laser was analyzed by X-ray photoelectron spectroscopy (XPS). The AFM photographs show that the micropattems are well-defined and of great consistency. Polymer properties and laser parameters related to LIL as well as laser ablation mechanisms are discussed in this technical note. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2307 / 2312
页数:6
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