Penile scarring with intracavernous injection therapy using prostaglandin E1: A risk factor analysis

Purpose: We attempted to identify risk factors for penile scarring in patients using prostaglandin El injection therapy. Materials and Methods: Records of 92 patients using prostaglandin El therapeutically were reviewed. With statistical methods, patients with (15) and without (77) scarring were compared. Results: No significant differences between the 2 groups were found regarding duration of followup, injection frequency, prostaglandin El dose per injection, total number of injections or total prostaglandin El dose. Patients with initial penile scarring did not have a significantly higher incidence of further scarring with prostaglandin E1. Conclusions: Penile scarring with prostaglandin El injection therapy is sporadic and unpredictable. Patients with initial penile scarring do not have a higher incidence of further scarring.