Testing for endothelial dysfunction

被引：113

作者：

Raitakari, OT

Celermajer, DS

机构：

[1] Royal Prince Alfred Hosp, Dept Cardiol, Sydney, NSW, Australia

[2] Univ Turku, Dept Clin Physiol, Turku, Finland

[3] Univ Turku, Turku PET Ctr, Turku, Finland

[4] Univ Sydney, Dept Med, Sydney, NSW 2006, Australia

来源：

ANNALS OF MEDICINE | 2000年 / 32卷 / 05期

基金：

芬兰科学院;

关键词：

atherosclerosis; endothelial physiology; vascular health;

D O I：

10.3109/07853890008995931

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Endothelial health is a key factor in normal cardiovascular homeostasis, and recent studies have revealed several important functions of the vascular endothelium that protect against atherothrombosis. These include control over arterial tone, coagulation, fibrinolysis, and vascular growth. Consequently, endothelial dysfunction has been implicated as an important event in the pathogenesis of atherosclerosis, coronary vasoconstriction, hypertension, and myocardial ischaemia. Therefore, there has been considerable research interest in diagnostic assays for the assessment of endothelium. This review outlines the current status of markers of endothelial dysfunction, particularly those related to vasomotor control, as well as circulating markers of vascular health.

引用

收藏

页码：293 / 304

页数：12

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