Extended-spectrum β-lactamase types in Klebsiella pneumoniae and Escherichia coli in two Greek hospitals

被引:52
作者
Tzelepi, E
Magana, C
Platsouka, E
Sofianou, D
Paniara, O
Legakis, NJ
Vatopoulos, AC
Tzouvelekis, LS [1 ]
机构
[1] Hellenic Pasteur Inst, Bacteriol Lab, Athens, Greece
[2] Evangelismos Gen Hosp, Dept Microbiol, Athens, Greece
[3] Hippokratio Gen Hosp, Dept Microbiol, Thessaloniki, Greece
[4] Univ Athens, Sch Med, Dept Epidemiol, GR-11527 Athens, Greece
[5] Univ Athens, Sch Med, Dept Microbiol, Athens 11521, Greece
关键词
Enterobacteriaceae; ESBL; beta-lactamases; SHV-5; CTX-M; IBC;
D O I
10.1016/S0924-8579(02)00361-8
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Seventy-nine Klebsiella pneumoniae and 124 Escherichia coli clinical strains, isolated consecutively during August-October 2001 in two Greek hospitals, were examined for production of extended-spectrum beta-lactamases (ESBLs). Seventy-one (35%) isolates (46 K pneumoniae and 25 E. coli) were ESBL-positive by phenotypic methods. Isoelectric focusing of beta-lactamases and PCR assays for bla genes showed that SHV-5-type ESBLs were the most frequent (45 isolates, 22%) followed by CTX-M (24 isolates, 12%) and IBC (three isolates, 1.5%). The latter two ESBL types may have been established recently in this setting. (C) 2002 Elsevier Science B.V. and the International Society of Chemotherapy. All rights reserved.
引用
收藏
页码:285 / 288
页数:4
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