Extended-spectrum β-lactamase types in Klebsiella pneumoniae and Escherichia coli in two Greek hospitals

被引：52

作者：

Tzelepi, E

Magana, C

Platsouka, E

Sofianou, D

Paniara, O

Legakis, NJ

Vatopoulos, AC

Tzouvelekis, LS ^{[1
]}

机构：

[1] Hellenic Pasteur Inst, Bacteriol Lab, Athens, Greece

[2] Evangelismos Gen Hosp, Dept Microbiol, Athens, Greece

[3] Hippokratio Gen Hosp, Dept Microbiol, Thessaloniki, Greece

[4] Univ Athens, Sch Med, Dept Epidemiol, GR-11527 Athens, Greece

[5] Univ Athens, Sch Med, Dept Microbiol, Athens 11521, Greece

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2003年 / 21卷 / 03期

关键词：

Enterobacteriaceae; ESBL; beta-lactamases; SHV-5; CTX-M; IBC;

D O I：

10.1016/S0924-8579(02)00361-8

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Seventy-nine Klebsiella pneumoniae and 124 Escherichia coli clinical strains, isolated consecutively during August-October 2001 in two Greek hospitals, were examined for production of extended-spectrum beta-lactamases (ESBLs). Seventy-one (35%) isolates (46 K pneumoniae and 25 E. coli) were ESBL-positive by phenotypic methods. Isoelectric focusing of beta-lactamases and PCR assays for bla genes showed that SHV-5-type ESBLs were the most frequent (45 isolates, 22%) followed by CTX-M (24 isolates, 12%) and IBC (three isolates, 1.5%). The latter two ESBL types may have been established recently in this setting. (C) 2002 Elsevier Science B.V. and the International Society of Chemotherapy. All rights reserved.

引用

页码：285 / 288

页数：4

共 17 条

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