Epithelial-mesenchymal transitions and hepatocarcinogenesis

被引：159

作者：

Jou, Janice ^{[1
]}

Diehl, Anna Mae ^{[1
]}

机构：

[1] Duke Univ, Div Gastroenterol, Durham, NC 27710 USA

来源：

JOURNAL OF CLINICAL INVESTIGATION | 2010年 / 120卷 / 04期

关键词：

CANCER; HEPATOCYTES; METASTASIS; INHIBITION; EXPRESSION; TWIST;

D O I：

10.1172/JCI42615

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

100103 [病原生物学]; 100218 [急诊医学];

摘要：

Epithelial-mesenchymal transitions (EMTs) are believed to play a role in invasion and metastasis of many types of tumors. In this issue of the JCI, Chen et al. show that a gene that has been associated with aggressive biology in hepatocellular carcinomas initiates a molecular cascade that results in EMT.

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收藏

页码：1031 / 1034

页数：4

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