Chiral synthesis of the CD ring unit of paclitaxel from D-glucal

被引：26

作者：

Momose, T ^{[1
]}

Setoguchi, M ^{[1
]}

Fujita, T ^{[1
]}

Tamura, H ^{[1
]}

Chida, N ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Appl Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 22期

关键词：

D O I：

10.1039/b006170k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The chiral synthesis of the fully functionalized CD ring unit of paclitaxel 3 is described; the three component coupling reaction of a cyclohexenone derived from d-glucal by way of Ferrier's carbocyclization with vinyl cuprate and formaldehyde effectively constructed the carbon framework of 3.

引用

页码：2237 / 2238

页数：2

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