Replicating by the clock

被引：121

作者：

Goren, A ^{[1
]}

Cedar, H ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Dept Cellular Biochem & Human Genet, IL-91120 Jerusalem, Israel

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2003年 / 4卷 / 01期

基金：

美国国家卫生研究院; 以色列科学基金会;

关键词：

D O I：

10.1038/nrm1008

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The eukaryotic genome is divided into well-defined DNA regions that are programmed to replicate at different times during S phase. Active genes are generally associated with early replication, whereas inactive genes replicate late. This expression pattern might be facilitated by the differential restructuring of chromatin at the time of replication in early or late S phase.

引用

页码：25 / 32

页数：8

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