Fast 3D T2-weighted MRI with Hadamard encoding in the slice select direction

A fast method to obtain 3-dimensional (3D) magnetic resonance imaging with long repetition times is presented. It can be used to obtain fast 3D MRI with for example T-2 or diffusion weighted imaging. The method uses a 3D multiple thin slab sequence with radio frequency encoding, preferably Hadamard encoding, in the slice select direction. The point-spread function of the Hadamard-encoded slices is close to ideal even at low encoding numbers. This allows the acquisition of 3D data volumes with tolerable image quality up to four times faster than is possible using Fourier phase encoding. The scope of the method includes both longitudinal and transverse encoding. Longitudinal encoding provides a better point spread function than transverse encoding, at the expense of having to discard one slice per slab. The method is demonstrated experimentally for 4th order longitudinal Hadamard encoding to obtain 3D T-2-weighted images. (C) 2000 Elsevier Science Inc. All rights reserved.