Biodegradable PLA-PGA polymers for tissue engineering in orthopaedics

被引：74

作者：

Agrawal, CM ^{[1
]}

Athanasiou, KA ^{[1
]}

Heckman, JD ^{[1
]}

机构：

[1] Univ Texas, Hlth Sci Ctr, Dept Orthopaed, San Antonio, TX 78284 USA

来源：

POROUS MATERIALS FOR TISSUE ENGINEERING | 1997年 / 250卷

关键词：

polylactic acid; polyglycolic acid; degradation; fabrication; porous; scaffolds;

D O I：

10.4028/www.scientific.net/MSF.250.115

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Polymers belonging to the family of polylactic acid (PLA) and polyglycolic acid (PGA) play an important role in the field of tissue engineering related to orthopaedics. These polymers degrade by hydrolysis and have a range of mechanical and physical properties. Their degradation characteristics depend on several parameters including their molecular structure, crystallinity, and copolymer ratio. Such polymers can be fashioned into porous scaffolds using a variety of techniques which have been described in this review paper. Although their future appears to be bright, several questions regarding the biocompatibility of these materials linger and have to be answered before their wide scale use.

引用

页码：115 / 128

页数：14

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