New polyketide peroxides from Okinawan marine sponge Plakortis sp.

被引：23

作者：

Fontana, A ^{[1
]}

Ishibashi, M ^{[1
]}

Kobayashi, J ^{[1
]}

机构：

[1] Hokkaido Univ, Fac Pharmaceut Sci, Sapporo, Hokkaido 060, Japan

来源：

TETRAHEDRON | 1998年 / 54卷 / 10期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/S0040-4020(97)10414-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New polyketide peroxides 2-4, isolated from an Okinawan sponge Plakortis sp., have been fully characterized by spectroscopic: and chemical methods. The absolute stereochemistries have been determined by analysis of MTPA esters of the acyclic derivatives. Compound 2 was cytotoxic against human epidermoid carcinoma KB and murine lymphoma L1210 cells. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2041 / 2048

页数：8

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