A natural surfactant from pig lungs

被引：9

作者：

Kubrusly, FS

Netto, SD

Iourtov, D

Raw, I

de Araujo, PS

机构：

[1] Inst Butantan, Ctr Biotecnol, BR-05503900 Sao Paulo, Brazil

[2] USP, Inst Quim, Dept Bioquim, Sao Paulo, Brazil

来源：

BIOTECHNOLOGY LETTERS | 2000年 / 22卷 / 15期

基金：

巴西圣保罗研究基金会;

关键词：

lung surfactant; purification technology; respiratory distress syndrome;

D O I：

10.1023/A:1005625804225

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

An exogenous natural lung surfactant obtained from minced pig lungs can be produced by a technology using a low cost, DEAE-cellulose adsorbent. This surfactant is composed mainly with phospholipids and the two hydrophobic polypeptides, SP-B and SP-C, both of which are necessary for optimal function of surfactants used for treatment of respiratory distress syndrome.

引用

页码：1251 / 1253

页数：3

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