Femoral osteomyelitis due to Aspergillus nidulans in a patient with chronic granulomatous disease

被引：33

作者：

Dotis, J

Panagopoulou, P

Filioti, J

Winn, R

Toptsis, C

Panteliadis, C

Roilides, E

机构：

[1] Aristotle Univ Thessaloniki, Dept Pediat 3, GR-54642 Thessaloniki, Greece

[2] Hippokrateion Hosp, Dept Orthoped, GR-54642 Thessaloniki, Greece

来源：

INFECTION | 2003年 / 31卷 / 02期

关键词：

D O I：

10.1007/s15010-002-2167-1

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

13 cases of osteomyelitis caused by Aspergillus nidulans have been previously reported in patients with chronic granulomatous disease (CGD). All of them have been associated with simultaneous pulmonary infection and have had an extremely poor outcome. We report an unusual case of femoral osteomyelitis due to A. nidulans in a 16-year-old male with CGD, without pulmonary involvement. Treatment with liposomal amphotericin B and granulocyte colony-stimulating factor as well as extensive surgical debridement followed by prolonged treatment with itraconazole resulted in an excellent clinical response.

引用

页码：121 / 124

页数：4

共 26 条

[1] THORACIC WALL INVASION SECONDARY TO PULMONARY ASPERGILLOSIS - COMPLICATION OF CHRONIC GRANULOMATOUS DISEASE OF CHILDHOOD [J].