Screening for Staphylococcus epidermidis markers discriminating between skin-flora strains and those responsible for infections of joint prostheses

被引：144

作者：

Galdbart, JO

Allignet, J

Tung, HS

Rydèn, C

El Solh, N

机构：

[1] Inst Pasteur, Ctr Natl Reference Staphylocoques, Unite Staphylocoques, F-75727 Paris 15, France

[2] Hop Beaujon, AP HP, Microbiol Serv, Clichy, France

[3] Ctr Biomed, Dept Med Biochem & Microbiol, Dept Med Infect Dis, Ctr Biomed, Uppsala, Sweden

来源：

JOURNAL OF INFECTIOUS DISEASES | 2000年 / 182卷 / 01期

关键词：

D O I：

10.1086/315660

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Fifty-four Staphylococcus epidermidis strains responsible for infections of joint prostheses and 23 strains isolated from skin flora were studied for markers of virulence, to discriminate invasive strains from normal flora. They were screened for binding to polystyrene and matrix proteins and for the presence of staphylococcal genes involved in adhesion. The ica operon involved in biofilm formation was the only marker discriminating between these 2 categories of strains.

引用

收藏

页码：351 / 355

页数：5

相关论文

共 16 条

[1] Tracking adhesion factors in Staphylococcus caprae strains responsible for human bane infections following implantation of orthopaedic material [J].

Allignet, J ;

Galdbart, JO ;

Morvan, A ;

Dyke, KGH ;

Vaudaux, P ;

Aubert, S ;

Desplaces, N ;

El Solh, N .

MICROBIOLOGY-UK, 1999, 145 :2033-2042

[2] Slime production and expression of the slime-associated antigen by staphylococcal clinical isolates [J].

Ammendolia, MG ;

Di Rosa, R ;

Montanaro, L ;

Arciola, CR ;

Baldassarri, L .

JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (10) :3235-3238

[3]

BARBIERFREBOURG N, 2000, J CLIN MICROBIOL, V38, P877

[4]

Christensen Gordon D., 1994, P45

[5] Phenotypic and genomic variation among Staphylococcus epidermidis strains infecting joint prostheses [J].

Galdbart, JO ;

Morvan, A ;

Desplaces, N ;

El Solh, N .

JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (05) :1306-1312

[6] Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis [J].

Heilmann, C ;

Schweitzer, O ;

Gerke, C ;

Vanittanakom, N ;

Mack, D ;

Gotz, F .

MOLECULAR MICROBIOLOGY, 1996, 20 (05) :1083-1091

[7] Evidence for autolysin-mediated primary attachment of Staphylococcus epidermidis to a polystyrene surface [J].

Heilmann, C ;

Hussain, M ;

Peters, G ;

Gotz, F .

MOLECULAR MICROBIOLOGY, 1997, 24 (05) :1013-1024

[8] Three new members of the serine-aspartate repeat protein multigene family of Staphylococcus aureus [J].

Josefsson, E ;

McCrea, KW ;

Ní Eidhin, D ;

O'Connell, D ;

Cox, J ;

Höök, M ;

Foster, TJ .

MICROBIOLOGY-UK, 1998, 144 :3387-3395

[9] Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope [J].

Navarre, WW ;

Schneewind, O .

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1999, 63 (01) :174-+

[10] A fibrinogen-binding protein of Staphylococcus epidermidis [J].

Nilsson, M ;

Frykberg, L ;

Flock, JI ;

Pei, L ;

Lindberg, M ;

Guss, B .

INFECTION AND IMMUNITY, 1998, 66 (06) :2666-2673