Common domains in the initiators of DNA replication in Bacteria, Archaea and Eukarya:: combined structural, functional and phylogenetic perspectives

被引:68
作者
Giraldo, R [1 ]
机构
[1] CSIC, Ctr Invest Biol, Dept Mol Microbiol, E-28006 Madrid, Spain
关键词
DNA replication initiators; origin binding proteins; AAA plus domain; winged-helix domain; phylogeny;
D O I
10.1016/S0168-6445(02)00145-6
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Although DNA replication is the universal process for the transmission of genetic information in all living organisms, until very recently evidence was lacking for a related structure and function in the proteins (initiators) that trigger replication in the three 'Life Domains' (Bacteria, Archaea and Eukarya). In this article new data concerning the presence of common features in the initiators of chromosomal replication in bacteria, archaea and eukaryotes are reviewed. Initiators are discussed in the light of: (i) The structure and function of their conserved ATPases Associated with various cellular Activities (AAA+) and winged-helix domains. (ii) The nature of the 7 macromolecular assemblies that they constitute at the replication origins. (iii) Their possible phylogenetic relationship, attempting to sketch the essentials of a hypothetical DNA replication initiator in the micro-organism proposed to be the ancestor of all living cells. (C) 2002 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码:533 / 554
页数:22
相关论文
共 220 条
[1]   Comparative genomics and evolution of proteins involved in RNA metabolism [J].
Anantharaman, V ;
Koonin, EV ;
Aravind, L .
NUCLEIC ACIDS RESEARCH, 2002, 30 (07) :1427-1464
[2]   Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication [J].
Aparicio, OM ;
Stout, AM ;
Bell, SP .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (16) :9130-9135
[3]   Components and dynamics of DNA replication complexes in S-cerevisiae: Redistribution of MCM proteins and Cdc45p during S phase [J].
Aparicio, OM ;
Weinstein, DM ;
Bell, SP .
CELL, 1997, 91 (01) :59-69
[4]   Domain combinations in archaeal, eubacterial and eukaryotic proteomes [J].
Apic, G ;
Gough, J ;
Teichmann, SA .
JOURNAL OF MOLECULAR BIOLOGY, 2001, 310 (02) :311-325
[5]   Crystal structure of a DNA-dependent RNA polymerase (DNA primase) [J].
Augustin, MA ;
Huber, R ;
Kaiser, JT .
NATURE STRUCTURAL BIOLOGY, 2001, 8 (01) :57-61
[6]   Polymerases and the replisome: Machines within machines [J].
Baker, TA ;
Bell, SP .
CELL, 1998, 92 (03) :295-305
[7]   Role of adenine nucleotides, molecular chaperones and chaperonins in stabilization of DnaA initiator protein of Escherichia coli [J].
Banecki, B ;
Kaguni, JM ;
Marszalek, J .
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1998, 1442 (01) :39-48
[8]   Cdc18 transcription and proteolysis couple S phase to passage through mitosis [J].
Baum, B ;
Nishitani, H ;
Yanow, S ;
Nurse, P .
EMBO JOURNAL, 1998, 17 (19) :5689-5698
[9]   The origin recognition complex: from simple origins to complex functions [J].
Bell, SP .
GENES & DEVELOPMENT, 2002, 16 (06) :659-672
[10]   DNA replication in eukaryotic cells [J].
Bell, SP ;
Dutta, A .
ANNUAL REVIEW OF BIOCHEMISTRY, 2002, 71 :333-374