New chemical synthesis of functionalized arylzinc compounds from aromatic or thienyl bromides under mild conditions using a simple cobalt catalyst and zinc dust

被引：157

作者：

Fillon, H ^{[1
]}

Gosmini, C ^{[1
]}

Périchon, J ^{[1
]}

机构：

[1] Univ Paris 12, UMR 7582 CNRS, Lab Electrochim Catalyze & Syth Organ, F-94320 Thiais, France

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 13期

关键词：

D O I：

10.1021/ja0289494

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new chemical method for the preparation of arylzinc intermediates is described in acetonitrile, on the basis of the activation of aryl bromides by low-valent cobalt species arising from the reduction of cobalt halide by zinc dust. This procedure allows for the synthesis of a variety of functionalized aryl- and thienylzinc species in good to excellent yields. The versatility and the simplicity of that original method represent an alternative to most known procedures.

引用

页码：3867 / 3870

页数：4

共 23 条

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