Sudden death due to auto-immune Addison's disease in a 12-year-old girl

被引：16

作者：

AlSabri, AM

Smith, N

Busuttil, A

机构：

[1] UNIV EDINBURGH,SCH MED,FORENS MED UNIT,EDINBURGH EH8 9AG,MIDLOTHIAN,SCOTLAND

[2] ROYAL HOSP SICK CHILDREN,EDINBURGH EH9 1LF,MIDLOTHIAN,SCOTLAND

来源：

INTERNATIONAL JOURNAL OF LEGAL MEDICINE | 1997年 / 110卷 / 05期

关键词：

Addison's disease; adreno-cortical insufficiency; adrenal glands; childhood;

D O I：

10.1007/s004140050085

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

A 12-year-old female suffering from adrenocortical insufficiency showed symptoms similar to a gastro-enteritis, and severe electrolytic and acid/base disturbances which progressed into cerebral oedema and death. Autopsy findings included depletion of the adrenal cortex, with enlargement and eosinophilia of surviving cells. In ante-mortem blood, anti-adrenal auto-antibodies were found and elevated levels of ACTH and cortisol with a low level of aldosterone.

引用

页码：278 / 280

页数：3

共 26 条

[1] 3 CASES OF CONGENITAL ADRENAL HYPOPLASIA - A CAUSE OF SALT-WASTING AND MORTALITY IN THE NEONATAL-PERIOD [J].