Iodinated Nanoscale Coordination Polymers as Potential Contrast Agents for Computed Tomography

被引：217

作者：

deKrafft, Kathryn E. ^{[1
]}

Xie, Zhigang ^{[1
]}

Cao, Guohua ^{[2
]}

Tran, Sylvie ^{[1
]}

Ma, Liqing ^{[1
]}

Zhou, Otto Z. ^{[2
]}

Lin, Wenbin ^{[1
]}

机构：

[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Dept Phys & Astron, Chapel Hill, NC 27599 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 52期

基金：

美国国家科学基金会;

关键词：

computed tomography; contrast agents; coordination polymers; iodine; nanoparticles; METAL-ORGANIC FRAMEWORKS; GOLD NANOPARTICLES; RAY;

D O I：

10.1002/anie.200904958

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nanoscale coordination polymers (NCPs), prepared with metal ions and an iodinated ligand, were synthesized using reverse-phase microemulsion techniques and rapid precipitation procedures. The NCPs carry high payloads of iodine (ca. 63 wt%) and have potential applications as a new class of contrast agents for computed tomography (CT), as demonstrated by phantom studies (see figure). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：9901 / 9904

页数：4

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