Biosynthesis of aminocyclitol-aminoglycoside antibiotics and related compounds

被引:98
作者
Flatt, Patricia M. [1 ]
Mahmud, Taifo [1 ]
机构
[1] Oregon State Univ, Dept Pharmaceut Sci, Corvallis, OR 97331 USA
关键词
D O I
10.1039/b603816f
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review covers the biosynthesis of aminocyclitol-aminoglycoside antibiotics and related compounds, particularly from the molecular genetic perspectives. 195 references are cited.
引用
收藏
页码:358 / 392
页数:35
相关论文
共 195 条
[1]   Identification of stsC, the gene encoding the L-glutamine:scyllo-inosose aminotransferase from streptomycin-producing Streptomycetes [J].
Ahlert, J ;
Distler, J ;
Mansouri, K ;
Piepersberg, W .
ARCHIVES OF MICROBIOLOGY, 1997, 168 (02) :102-113
[2]   Involvement of AfsA in A-factor biosynthesis as a key enzyme [J].
Ando, N ;
Matsumori, N ;
Sakuda, S ;
Beppu, T ;
Horinouchi, S .
JOURNAL OF ANTIBIOTICS, 1997, 50 (10) :847-852
[3]   ISOLATION ON TREHALAMINE, THE AGLYCON OF TREHAZOLIN, FROM MICROBIAL BROTHS AND CHARACTERIZATION OF TREHAZOLIN RELATED-COMPOUNDS [J].
ANDO, O ;
NAKAJIMA, M ;
HAMANO, K ;
ITOI, K ;
TAKAHASHI, S ;
TAKAMATSU, Y ;
SATO, A ;
ENOKITA, R ;
OKAZAKI, T ;
HARUYAMA, H ;
KINOSHITA, T .
JOURNAL OF ANTIBIOTICS, 1993, 46 (07) :1116-1125
[4]   TREHAZOLIN, A NEW TREHALASE INHIBITOR [J].
ANDO, O ;
SATAKE, H ;
ITOI, K ;
SATO, A ;
NAKAJIMA, M ;
TAKAHASHI, S ;
HARUYAMA, H ;
OHKUMA, Y ;
KINOSHITA, T ;
ENOKITA, R .
JOURNAL OF ANTIBIOTICS, 1991, 44 (10) :1165-1168
[5]   Biosynthetic studies on the α-glucosidase inhibitor acarbose:: the chemical synthesis of isotopically labeled 2-epi-5-epi-valiolone analogs [J].
Arakawa, K ;
Bowers, SG ;
Michels, B ;
Trin, V ;
Mahmud, T .
CARBOHYDRATE RESEARCH, 2003, 338 (20) :2075-2082
[6]   Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid:: The RifN protein specifically converts kanosamine into kanosamine 6-phosphate [J].
Arakawa, K ;
Müller, R ;
Mahmud, T ;
Yu, TW ;
Floss, HG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (36) :10644-10645
[7]   EFFECT OF VALIDAMYCINS ON GLYCOHYDROLASES OF RHIZOCTONIA-SOLANI [J].
ASANO, N ;
YAMAGUCHI, T ;
KAMEDA, Y ;
MATSUI, K .
JOURNAL OF ANTIBIOTICS, 1987, 40 (04) :526-532
[8]   Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699 [J].
August, PR ;
Tang, L ;
Yoon, YJ ;
Ning, S ;
Muller, R ;
Yu, TW ;
Taylor, M ;
Hoffmann, D ;
Kim, CG ;
Zhang, XH ;
Hutchinson, CR ;
Floss, HG .
CHEMISTRY & BIOLOGY, 1998, 5 (02) :69-79
[9]   Functional analysis of the validamycin biosynthetic gene cluster and engineered production of validoxylamine A [J].
Bai, L ;
Li, L ;
Xu, H ;
Minagawa, K ;
Yu, Y ;
Zhang, YR ;
Zhou, XF ;
Fioss, HG ;
Mahmud, T ;
Deng, ZX .
CHEMISTRY & BIOLOGY, 2006, 13 (04) :387-397
[10]   RIBOSTAMYCIN, AS AN INTERMEDIATE IN BIOSYNTHESIS OF NEOMYCIN [J].
BAUD, H ;
BETENCOURT, A ;
PEYRE, M ;
PENASSE, L .
JOURNAL OF ANTIBIOTICS, 1977, 30 (09) :720-723