Synthesis, photophysical and photochemical aspects of phthalocyanines for photodynamic therapy

被引：171

作者：

Tedesco, AC ^{[1
]}

Rotta, JCG ^{[1
]}

Lunardi, CN ^{[1
]}

机构：

[1] Univ Sao Paulo, FFCLRP, Dept Chem, Photobiol & Photomed Res Grp, BR-14040901 Ribeirao Preto, SP, Brazil

来源：

CURRENT ORGANIC CHEMISTRY | 2003年 / 7卷 / 02期

关键词：

D O I：

10.2174/1385272033373076

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Phthalocyanines exhibit a number of unique properties that make them of great interest in different scientific and technological areas. One of the most promising fields is the use of metallo phthalocyanine derivatives as photosensitizers for Photodynamic Therapy (PDT). Using PDT against cancer involves the irradiation of tumors with visible light following selective uptake of a photosensitizer by the tumor tissue. This review briefly summarizes the photophysical, photochemical and synthetic aspects of phthalocyanines compounds, evaluating their application for PDT.

引用

页码：187 / 196

页数：10

共 100 条

[1] Targeting of the tumor microcirculation by photodynamic therapy with a synthetic porphycene [J].