2-chloro-4,6-dimethoxy-1,3,5-triazine: A new effective and convenient coupling reagent for cephalosporin derivatives

被引：13

作者：

Lee, HW ^{[1
]}

Kang, TW ^{[1
]}

Cha, KH ^{[1
]}

Kim, EN ^{[1
]}

Choi, NH ^{[1
]}

Kim, JW ^{[1
]}

Hong, CI ^{[1
]}

机构：

[1] Chong Kun Dang Corp, Res Inst, Seoul 152600, South Korea

来源：

SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 08期

关键词：

D O I：

10.1080/00397919808006831

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chloro-4,6-dimethoxy-1,3,5-triazine(CDMT) 2 was reacted with 2-(2-amino-4-thiazolyl)-2-syn-alkoxyiminoacetic acid 1 to give an active ester intermediate 3.

引用

页码：1339 / 1349

页数：11

共 12 条

[1] BODANAZKY M, 1976, PEPTIDE SYNTHESIS
[2] BODANSZKY M, 1979, PEPTIDES, V1
[3] Bodanszky M., 1983, PEPTIDES, V5, P111
[4] REACTION OF N-HYDROXYSUCCINIMIDE WITH DICYCLOHEXYLCARBODIIMIDE
GROSS, H
BILK, L
[J]. TETRAHEDRON, 1968, 24 (24) : 6935 - &
[5] ITOH M, 1974, TETRAHEDRON LETT, P3089
[6] BENZOTRIAZOL-1-YL DIETHYL PHOSPHATE - A NEW CONVENIENT COUPLING REAGENT FOR THE SYNTHESIS OF AMIDES AND PEPTIDES
KIM, S
CHANG, H
KO, YK
[J]. TETRAHEDRON LETTERS, 1985, 26 (10) : 1341 - 1342
[7] LIU RH, 1983, J CHROMATOGR, V217, P309
[8] OGLIARUSO MA, CHEM ACID DERIVATIVE
[9] TAKADA K, 1983, TETRAHEDRON LETT, V24, P4451
[10] UDEA M, 1983, SYNTHESIS-STUTTGART, P908

← 1 2 →