A physical model for studying adhesion between a living cell and a spherical functionalized substrate

被引:6
作者
Canetta, E
Leyrat, A
Verdier, C
机构
[1] Univ Grenoble, Lab Rheol, UJF, INPG, F-38041 Grenoble 9, France
[2] CNRS, UMR 5520, F-38041 Grenoble, France
关键词
adhesion; binding kinetics; rupture force; multiple bonds;
D O I
10.1016/S0895-7177(03)00124-9
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
A new microadhesion experiment is analysed in the framework of a stochastic model. Particular attention is focused on the adhesion between a functionalized spherical microsphere and a cell grown on a substrate. The parameters governing the dynamics of failure are deduced from the theory and the geometry of the system. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1121 / 1129
页数:9
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