Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates

被引：62

作者：

Leonard, EE

Takata, T

Blaser, MJ

Falkow, S

Tompkins, LS

Gaynor, EC

机构：

[1] Stanford Univ, Med Ctr, Dept Microbiol & Immunol, Div Infect Dis, Stanford, CA 94305 USA

[2] Stanford Univ, Dept Geog Med, Stanford, CA 94305 USA

[3] NYU, Dept Med, New York, NY 10016 USA

[4] NYU, Dept Microbiol, New York, NY 10016 USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2003年 / 187卷 / 04期

关键词：

D O I：

10.1086/368268

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Findings from use of an open-reading frame-specific Campylobacter jejuni DNA microarray to investigate genetic diversity among clinical isolates associated with 5 independent clusters of infection were compared with data from random amplified polymeric DNA (RAPD) and Penner serotyping analyses. The DNA microarray provides a highly specific epidemiological typing tool for analysis of C. jejuni isolates and reveals both divergent and highly conserved gene classes among isolates.

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页码：691 / 694

页数：4

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