Levels of vascular cell adhesion molecule-1 and endothelin-1 in ischemic stroke: A longitudinal prospective study

被引：19

作者：

Brondani, Rosane ^{[1
]}

Rieder, Carlos R. M. ^{[1
]}

Valente, Denise ^{[1
]}

Araujo, Luis F. ^{[1
]}

Clausell, Nadine ^{[1
]}

机构：

[1] Univ Fed Rio Grande Sul, Grad Program Clin Med, Div Neurol, Hosp Clin Porto Alegre, BR-90046900 Porto Alegre, RS, Brazil

来源：

CLINICAL BIOCHEMISTRY | 2007年 / 40卷 / 3-4期

关键词：

cerebral ischemia; inflammation; adhesion molecules; endothelin-1; vascular endothelium;

D O I：

10.1016/j.clinbiochem.2006.09.014

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Objectives: To determine levels of vascular cellular adhesion molecule (VCAM)-1 and endothelin (ET)-1 in patients with stroke. Design and methods: Thirty-four patients were prospectively studied. Plasma levels of VCAM-1 and ET-1 were measured by ELISA within 72 h of the event, at 7 and 90 days. Results: Levels of VCAM-1 increased overtime, whereas ET-1 values were initially and persistently elevated. Conclusions: Increased circulating levels of VCAM-1 and ET -1 are present during stroke. (c) 2006 The Canadian Society of Clinical Chemists. All rights reserved.

引用

收藏

页码：282 / 284

页数：3

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