Pharmacology of drug transfer across the placenta

被引:39
作者
Garland, M [1 ]
机构
[1] Columbia Univ Coll Phys & Surg, Dept Pediat, Div Neonatal Perinatal Med, New York, NY 10032 USA
关键词
D O I
10.1016/S0889-8545(05)70356-9
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Principles of drug disposition in pregnancy allow for estimations of fetal drug exposure following maternal gestation; therefore, prediction may be determined as to the effect of the drug on the fetus based on a knowledge of the dose response. This facilitates the safe use of drugs for therapeutic purposes and defines the risk for adverse effects on the fetus.
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页码:21 / +
页数:23
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